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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.45 | Total: $157.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 100 | $16.65 | Total: $1,665.00 |
Overview
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora ABC with IC50 values of 5 nM, 4 nM, and 1 nM, respectively. It exhibits over 10-fold selectivity for Aurora kinases compared to p38?, Tyk2, JNK2, Met, and Tie2. [Phase 1].
Chemical Properties
| Molecular Formula | C28H21N7OS |
| Molecular Weight | 503.58 |
| CAS Numbers | 945595-80-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1csc(c1)-c1nnc(Nc2ccc(Oc3ncccc3-c3ccnc(N)n3)cc2)c2ccccc12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Payton M, et al, Cancer Res, 2010, 70[23], 9846-19854.