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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790ML858R mutant respectively.
Chemical Properties
| Molecular Formula | C25H17F3N4O3 |
| Molecular Weight | 478.42 |
| CAS Numbers | 1446090-79-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H][C@]12Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@]1([H])[C@@H]2c1nc2ccc(cc2[nH]1)C(F)(F)F |
Storage and Handling
0C Short Term, -20C Long Term
References
Tang Z, et al. Mol Cancer Ther. 2015, 14[10] 2187-97.