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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $119.00 | Total: $595.00 |
| 1 | 10 | $100.80 | Total: $1,008.00 |
| 1 | 25 | $85.40 | Total: $2,135.00 |
| 1 | 50 | $72.80 | Total: $3,640.00 |
| 1 | 100 | $63.00 | Total: $6,300.00 |
Overview
Ifebemtinib (BI-853520) is an orally active and potent inhibitor of adhesion plaque kinase (FAK) (IC50=1 nM) with anti-tumour activity that inhibits globule formation and in situ tumour growth in malignant pleural mesotheliomas, and may be useful for the study of breast and ovarian cancer.
Chemical Properties
| Molecular Formula | C28H28F4N6O4 |
| Molecular Weight | 588.55 |
| CAS Numbers | 1227948-82-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc(c(Oc2cccc3CN(C)C(=O)c23)n1)C(F)(F)F |
Storage and Handling
0C Short Term, -20C Long Term
References
Hirt UA, et al. Efficacy of the highly selective focal adhesion kinase inhibitor BI 853520 in adenocarcinoma xenograft models is linked to a mesenchymal tumor phenotype. Oncogenesis. 2018 Feb 23;7[2] 21.