DSM421

DSM421

AT27214

CAS 2011769-21-2

More details

1000 Items

$217.10

$217.10 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $141.95 Total: $709.75
110 $120.24 Total: $1,202.40
125 $101.87 Total: $2,546.75
150 $86.84 Total: $4,342.00
1100 $75.15 Total: $7,515.00

Overview

DSM421 (DSM-421) is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shown activity against field isolates of both P. falciparum and P. vivax.

Chemical Properties

Molecular FormulaC14H11F5N6
Molecular Weight358.27
CAS Numbers2011769-21-2
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN(C=1N2C(=NC(C(C)(F)F)=N2)N=C(C)C1)C=3C=CC(C(F)(F)F)=NC3

Storage and Handling

0C Short Term, -20C Long Term

References

Phillips MA, et al. A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria. ACS Infect Dis. 2016;2[12] 945-957.