Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
GDC-0326 is a potent and selective inhibitor of the ?-isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor).
Chemical Properties
| Molecular Formula | C19H22N6O3 |
| Molecular Weight | 382.42 |
| CAS Numbers | 1282514-88-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)n1ncnc1-c1cn2CCOc3cc(O[C@@H](C)C(N)=O)ccc3-c2n1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Heffron TP., et al. The Rational Design of Selective Benzoxazepin Inhibitors of the ?-Isoform of Phosphoinositide 3-Kinase Culminating in the Identification of [S]-2-[[2-[1-Isopropyl-1H-1,2,4-triazol-5-yl]-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]oxy]propanamide [GDC-0326]. J Med Chem. 2016 Feb 11;59[3] 985-1002.