Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $240.55 | Total: $1,202.75 |
| 1 | 10 | $203.76 | Total: $2,037.60 |
| 1 | 25 | $172.63 | Total: $4,315.75 |
| 1 | 50 | $147.16 | Total: $7,358.00 |
| 1 | 100 | $127.35 | Total: $12,735.01 |
Overview
Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication, demonstrating anti-HIV activity with an EC50 of 100 pM in MT-4 cells.
Chemical Properties
| Molecular Formula | C39H32ClF10N7O5S2 |
| Molecular Weight | 968.28 |
| CAS Numbers | 2189684-44-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H][C@]12C[C@@]1([H])C(F)(F)c1c2c(nn1CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1nc(ccc1-c1ccc(Cl)c2c(NS(C)(=O)=O)nn(CC(F)(F)F)c12)C#CC(C)(C)S(C)(=O)=O)C(F)(F)F |
Storage and Handling
0C Short Term, -20C Long Term
References
John O Link, et al. Clinical targeting of HIV capsid protein with a long-acting small molecule. Nature. 2020 Jul 1.