Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
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- Customized Screening Library
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- Proteins and Antibodies
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $95.20 | Total: $476.00 |
| 1 | 10 | $80.64 | Total: $806.40 |
| 1 | 25 | $68.32 | Total: $1,708.00 |
| 1 | 50 | $58.24 | Total: $2,912.00 |
| 1 | 100 | $50.40 | Total: $5,040.00 |
Overview
Lartesertib (ATM Inhibitor-5) is an inhibitor of serinethreonine protein kinase ATM with potential anticancer activity for the study of lung cancer.
Chemical Properties
| Molecular Formula | C23H21FN6O3 |
| Molecular Weight | 448.45 |
| CAS Numbers | 2495096-26-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cncc(F)c1-n1c2c(cnc3cc(OC)c(cc23)-c2cn(C)nc2C)n(C)c1=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Turchick A,et al. Selective Inhibition of ATM-dependent Double-strand Break Repair and Checkpoint Control Synergistically Enhances the Efficacy of ATR Inhibitors. Mol Cancer Ther. 2023 Jul 5;22[7] 859-872.