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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $88.40 | Total: $442.00 |
| 1 | 10 | $74.88 | Total: $748.80 |
| 1 | 25 | $63.44 | Total: $1,586.00 |
| 1 | 50 | $54.08 | Total: $2,704.00 |
| 1 | 100 | $46.80 | Total: $4,680.00 |
Overview
Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively).
Chemical Properties
| Molecular Formula | C12H12FN5O3 |
| Molecular Weight | 293.25 |
| CAS Numbers | 865363-93-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Nc1nc(F)nc2n(cnc12)[C@H]1C[C@H](O)[C@@](CO)(O1)C#C |
Storage and Handling
0C Short Term, -20C Long Term
References
Ohrui H, et al. 2'-deoxy-4'-C-ethynyl-2-fluoroadenosine, a nucleoside reverse transcriptase inhibitor, is highly potent against all human immunodeficiency viruses type 1 and has low toxicity. Chem Rec. 2006;6[3] 133-43.