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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $55.25 | Total: $276.25 |
| 1 | 10 | $46.80 | Total: $468.00 |
| 1 | 25 | $39.65 | Total: $991.25 |
| 1 | 50 | $33.80 | Total: $1,690.00 |
| 1 | 100 | $29.25 | Total: $2,925.00 |
Overview
Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29803 nM for JAK12).
Chemical Properties
| Molecular Formula | C14H21N5O2S |
| Molecular Weight | 323.41 |
| CAS Numbers | 1622902-68-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCCS(=O)(=O)N[C@H]1C[C@H](C1)N(C)c1ncnc2[nH]ccc12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Vazquez ML, et al. Identification of N-{cis-3-[Methyl[7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclobutyl}propane-1-sulfonamide [PF-04965842] A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases. J Med Chem. 2018 Feb 8;61[3] 1130-1152.