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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $90.10 | Total: $450.50 |
| 1 | 10 | $76.32 | Total: $763.20 |
| 1 | 25 | $64.66 | Total: $1,616.50 |
| 1 | 50 | $55.12 | Total: $2,756.00 |
| 1 | 100 | $47.70 | Total: $4,770.00 |
Overview
Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activity and dimerisation and has potent activity against multiple protease inhibitor (PI) HIV-1 isolates (IC50 of 66-410 nM). Tipranavir inhibits SARS-CoV-2 3CLpro activity.
Chemical Properties
| Molecular Formula | C31H33F3N2O5S |
| Molecular Weight | 602.66 |
| CAS Numbers | 174484-41-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCC[C@@]1(CCc2ccccc2)CC(O)=C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c2)C(=O)O1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Aoki M, et al. Loss of the protease dimerization inhibition activity of tipranavir [TPV] and its association with the acquisition of resistance to TPV by HIV-J Virol. 2012 ; 86[24] 13384-13396.