Atuzabrutinib

Atuzabrutinib

AT39056

CAS 1581714-49-9

More details

1000 Items

$209.30

$209.30 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $136.85 Total: $684.25
110 $115.92 Total: $1,159.20
125 $98.21 Total: $2,455.25
150 $83.72 Total: $4,186.00
1100 $72.45 Total: $7,245.00

Overview

Atuzabrutinib (SAR 444727) is a selective Bruton's tyrosine kinase (Btk) inhibitor that inhibits intra-neutrophilic neutrophilic granulocytes through inhibition of the adhesion receptor signaling pathway, and can be used to study autoimmune disorders such as arthritis in rheumatoid rodents and pemphigus vulgaris.

Chemical Properties

Molecular FormulaC30H30FN7O2
Molecular Weight539.6
CAS Numbers1581714-49-9
SolubilityDMSO
Purity98% by HPLC
SMILES CodeNC1=C2C(N(N=C2C3=C(F)C=C(OC4=CC=CC=C4)C=C3)[C@H]5CN(C(C(=CC(C)(C)C)C#N)=O)CCC5)=NC=N1

Storage and Handling

0C Short Term, -20C Long Term

References

Steven GOURLAY, et al. Treatment of pemphigus. WO2016100914A1.