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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $23.80 | Total: $119.00 |
| 1 | 10 | $20.16 | Total: $201.60 |
| 1 | 25 | $17.08 | Total: $427.00 |
| 1 | 50 | $14.56 | Total: $728.00 |
| 1 | 100 | $12.60 | Total: $1,260.00 |
Overview
TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
Chemical Properties
| Molecular Formula | C17H22ClFN6O |
| Molecular Weight | 380.85 |
| CAS Numbers | 1952251-28-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(F)c2CNC(=O)c12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Lam B, et al. Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase [SYK]. Bioorg Med Chem Lett. 2016 Dec 15;26[24] 5947-5950.