Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $505.75 | Total: $2,528.75 |
| 1 | 10 | $428.40 | Total: $4,284.00 |
| 1 | 25 | $362.95 | Total: $9,073.75 |
| 1 | 50 | $309.40 | Total: $15,470.00 |
| 1 | 100 | $267.75 | Total: $26,775.01 |
Overview
JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 ?M) intended for the treatment of organ transplantation rejection, graft-versus-host reaction post-transplantation, autoimmune disorders, allergic diseases, and chronic myeloproliferative disorders.
Chemical Properties
| Molecular Formula | C17H20N6O |
| Molecular Weight | 324.38 |
| CAS Numbers | 1263774-57-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N#CCC(=O)N1CC(C)C12CN(C=3N=CN=C4NC=CC43)CCC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
NOJI, Satoru, et al. NITROGEN-CONTAINING SPIRO-RING COMPOUND AND MEDICINAL USE OF SAME. WO2011013785A1.