Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $51.85 | Total: $259.25 |
| 1 | 10 | $43.92 | Total: $439.20 |
| 1 | 25 | $37.21 | Total: $930.25 |
| 1 | 50 | $31.72 | Total: $1,586.00 |
| 1 | 100 | $27.45 | Total: $2,745.00 |
Overview
NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
Chemical Properties
| Molecular Formula | C35H39F3N8O3 |
| Molecular Weight | 676.73 |
| CAS Numbers | 1202055-32-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCc1cccc(CC)c1NC(=O)c1nn(C)c-2c1CCc1cnc(Nc3ccc(cc3OC(F)(F)F)C(=O)NC3CCN(C)CC3)nc-21 |
Storage and Handling
0C Short Term, -20C Long Term
References
Colombo R, et al. Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase. Cancer Res. 2010 Dec 15;70[24] 10255-64.