Categories
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- Protein Control Ligand
- Pathway Inhibitors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $65.45 | Total: $327.25 |
| 1 | 10 | $55.44 | Total: $554.40 |
| 1 | 25 | $46.97 | Total: $1,174.25 |
| 1 | 50 | $40.04 | Total: $2,002.00 |
| 1 | 100 | $34.65 | Total: $3,465.00 |
Overview
PK68 is an effective and selective inhibitor of type II receptor-interacting kinase 1 (RIPK1, IC50 = 90?nM). PK68 can be used for research on the treatment of inflammatory disorders and cancer metastasis.
Chemical Properties
| Molecular Formula | C22H24N4O3S |
| Molecular Weight | 424.52 |
| CAS Numbers | 2173556-69-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(=O)Nc1nc2ccc(cc2s1)-c1cnc(C)c(NC(=O)OC2CCCCC2)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Hou J, et al. Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis. Cell Death Dis. 2019 Jun 24;10[7] 493.