ROCK inhibitor-2

ROCK inhibitor-2

AT12746

CAS 1127308-52-4

More details

999 Items

$66.30

$66.30 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $43.35 Total: $216.75
110 $36.72 Total: $367.20
125 $31.11 Total: $777.75
150 $26.52 Total: $1,326.00
1100 $22.95 Total: $2,295.00

Overview

ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2, with IC50 values of 17 nM and 2 nM, respectively.

Chemical Properties

Molecular FormulaC21H20N2O2
Molecular Weight332.4
CAS Numbers1127308-52-4
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1cccc(c1)[C@@H](C)NC(=O)c1ccc(cc1)-c1ccncc1

Storage and Handling

0C Short Term, -20C Long Term

References

Hobson AD, et al. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based DrugDesign. J Med Chem. 2018 Dec 27;61[24] 11074-11100.

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