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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $105.40 | Total: $527.00 |
| 1 | 10 | $89.28 | Total: $892.80 |
| 1 | 25 | $75.64 | Total: $1,891.00 |
| 1 | 50 | $64.48 | Total: $3,224.00 |
| 1 | 100 | $55.80 | Total: $5,580.00 |
Overview
CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.
Chemical Properties
| Molecular Formula | C15H15FN6O2S2 |
| Molecular Weight | 394.45 |
| CAS Numbers | 1421693-22-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CNc1nc(C)c(s1)-c1nc(Nc2cccc(c2)S(N)(=O)=O)ncc1F |
Storage and Handling
0C Short Term, -20C Long Term
References
Xie S, et al. Antitumor action of CDK inhibitor LS-007 as a single agent and in combination with ABT-199 against human acute leukemia cells. Acta Pharmacol Sin. 2016 Nov;37[11] 1481-1489.