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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $56.95 | Total: $284.75 |
| 1 | 10 | $48.24 | Total: $482.40 |
| 1 | 25 | $40.87 | Total: $1,021.75 |
| 1 | 50 | $34.84 | Total: $1,742.00 |
| 1 | 100 | $30.15 | Total: $3,015.00 |
Overview
DK419 is an orally active inhibitor of Wnt?-catenin signaling, with an IC50 of 0.19 ?M. DK419 decreases protein lelvels of Axin2, ?-catenin, c-Myc, Cyclin D1 and Survivin.It also induces production of pAMPK.
Chemical Properties
| Molecular Formula | C16H8ClF6N3O |
| Molecular Weight | 407.7 |
| CAS Numbers | 2102672-22-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC(F)(F)c1nc2cc(Cl)cc(C(=O)Nc3ccc(cc3)C(F)(F)F)c2[nH]1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Wang J, et al. Identification of DK419, a potent inhibitor of Wnt?-catenin signaling and colorectal cancer growth. Bioorg Med Chem. 2018 Nov 1;26[20] 5435-5442.