Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $119.85 | Total: $599.25 |
| 1 | 10 | $101.52 | Total: $1,015.20 |
| 1 | 25 | $86.01 | Total: $2,150.25 |
| 1 | 50 | $73.32 | Total: $3,666.00 |
| 1 | 100 | $63.45 | Total: $6,345.00 |
Overview
GSK251 is a novel, orally bioavailable inhibitor of PI3K?, exhibiting high potency and selectivity, with a unique binding mode.
Chemical Properties
| Molecular Formula | C29H37FN6O4S |
| Molecular Weight | 584.71 |
| CAS Numbers | 2125968-05-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ncc(cc1S(=O)(=O)Nc1ccnc(c1)-c1ccc(CN2CCN(CC2)C(C)C)cc1F)N1CCOCC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Down K, et al. Discovery of GSK251 A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3K? with a Novel Binding Mode. J Med Chem. 2021 Sep 23;64[18] 13780-13792.