Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $168.30 | Total: $841.50 |
| 1 | 10 | $142.56 | Total: $1,425.60 |
| 1 | 25 | $120.78 | Total: $3,019.50 |
| 1 | 50 | $102.96 | Total: $5,148.00 |
| 1 | 100 | $89.10 | Total: $8,910.00 |
Overview
AS-1763 is an orally available and selective BTK inhibitor with an IC50 of 0.85 nM.
Chemical Properties
| Molecular Formula | C33H31FN6O3 |
| Molecular Weight | 578.64 |
| CAS Numbers | 2227211-00-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1C=2C(F)=CC(=CC2C=CN1C3=CC=CC(C=4N=C(N=C5NC(=CC54)C6=CCN(CC6)C7COC7)N)=C3CO)C8CC8 |
Storage and Handling
0C Short Term, -20C Long Term
References
Kawahata W, et al. Discovery of AS-1763 A Potent, Selective, Noncovalent, and Orally Available Inhibitor of Bruton's Tyrosine Kinase. J Med Chem. 2021 Oct 14;64[19] 14129-14141.