R-IMPP

R-IMPP

AT4058

CAS 2133832-83-2

More details

1000 Items

$44.20

$44.20 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $28.90 Total: $144.50
110 $24.48 Total: $244.80
125 $20.74 Total: $518.50
150 $17.68 Total: $884.00
1100 $15.30 Total: $1,530.00

Overview

R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.

Chemical Properties

Molecular FormulaC24H27N3O2
Molecular Weight389.49
CAS Numbers2133832-83-2
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1ccc(CCC(=O)N([C@@H]2CCCNC2)c2nccc3ccccc23)cc1

Storage and Handling

0C Short Term, -20C Long Term

References

Petersen DN., et al. A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein Translation. Cell Chem Biol. 2016 Nov 17;23[11] 1362-1371.