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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $27.20 | Total: $136.00 |
| 1 | 10 | $23.04 | Total: $230.40 |
| 1 | 25 | $19.52 | Total: $488.00 |
| 1 | 50 | $16.64 | Total: $832.00 |
| 1 | 100 | $14.40 | Total: $1,440.00 |
Overview
AS-2444697 is an inhibitor of IRAK-4 (C50 = 21 nM). AS-2444697 exhibits renoprotective effects through anti-inflammatory action. AS-2444697 potently inhibits human and rat IRAK-4 activity.
Chemical Properties
| Molecular Formula | C19H21ClN6O4 |
| Molecular Weight | 432.86 |
| CAS Numbers | 1287665-60-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cc1cc(ccn1)-c1nc(co1)C(=O)Nc1cn(nc1C(N)=O)C1CCOCC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Mitsuhiro Kondo, et al. Renoprotective effects of novel interleukin-1 receptor-associated kinase 4 inhibitor AS2444697 through anti-inflammatory action in 56 nephrectomized rats. Naunyn Schmiedebergs Arch Pharmacol. 2014 Oct;387[10] 909-19.