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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $36.55 | Total: $182.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 100 | $19.35 | Total: $1,935.00 |
Overview
AZ32 is an orally bioavailable, blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for the ATM enzyme and an IC50 of 0.31 ?M for ATM in cells.
Chemical Properties
| Molecular Formula | C20H16N4O |
| Molecular Weight | 328.37 |
| CAS Numbers | 2288709-96-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CNC(=O)c1ccc(cc1)-c1cnc2cnc(cn12)-c1ccccc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Karlin J, et al. Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor [AZ32] Radiosensitizes Intracranial Gliomas in Mice. Mol Cancer Ther. 2018 Aug;17[8] 1637-1647.