Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $43.35 | Total: $216.75 |
| 1 | 10 | $36.72 | Total: $367.20 |
| 1 | 25 | $31.11 | Total: $777.75 |
| 1 | 50 | $26.52 | Total: $1,326.00 |
| 1 | 100 | $22.95 | Total: $2,295.00 |
Overview
BIBF0775 is a selective TGF? type I receptor (Alk5) inhibitor (IC50: 34 nM).
Chemical Properties
| Molecular Formula | C31H34N4O2 |
| Molecular Weight | 494.63 |
| CAS Numbers | 334951-90-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCN(C)C(=O)c1ccc2C(=C(Nc3ccc(CN4CCCCC4)cc3)c3ccccc3)C(=O)Nc2c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Roth GJ, et al. Design, synthesis, and evaluation of indolinones as inhibitors of the transforming growth factor ? receptor I [TGF?RI]. J Med Chem. 2010 Oct 28;53[20] 7287-95.