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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $39.95 | Total: $199.75 |
| 1 | 10 | $33.84 | Total: $338.40 |
| 1 | 25 | $28.67 | Total: $716.75 |
| 1 | 50 | $24.44 | Total: $1,222.00 |
| 1 | 100 | $21.15 | Total: $2,115.00 |
Overview
ARN-3236 is an orally active and selective inhibitor of salt-inducible kinase 2 (SIK2), with IC50 values of <1 nM for SIK2, 21.63 nM for SIK1, and 6.63 nM for SIK3. ARN-3236 exhibits anti-cancer activity.
Chemical Properties
| Molecular Formula | C19H16N2O2S |
| Molecular Weight | 336.41 |
| CAS Numbers | 1613710-01-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ccc(-c2c[nH]c3nccc(-c4ccsc4)c23)c(OC)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Zhou J , Alfraidi A , Zhang S , et al. A novel compound ARN-3236 inhibits Salt Inducible Kinase 2 and sensitizes ovarian cancer cell lines and xenografts to paclitaxel[J]. Clinical Cancer Research, 2016 1078-0432.CCR-16-1562.