JNK-IN-11

JNK-IN-11

AT60534

CAS 676594-38-0

More details

1000 Items

$42.90

$42.90 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $28.05 Total: $140.25
110 $23.76 Total: $237.60
125 $20.13 Total: $503.25
150 $17.16 Total: $858.00
1100 $14.85 Total: $1,485.00

Overview

JNK-IN-11 (compound 1) is a potent inhibitor of JNK, with IC50 values of 2.2 ?M, 21.4 ?M, and 1.8 ?M for JNK1, JNK2, and JNK3, respectively, showing potential for Alzheimer's and Parkinson's disease research.

Chemical Properties

Molecular FormulaC12H11NO3S2
Molecular Weight281.35
CAS Numbers676594-38-0
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(OC)C=1SC=CC1NC(=O)CC=2SC=CC2

Storage and Handling

0C Short Term, -20C Long Term

References

Hom RK, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg Med Chem Lett. 2010 Dec 15;20[24] 7303-7.