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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $83.30 | Total: $416.50 |
| 1 | 10 | $70.56 | Total: $705.60 |
| 1 | 25 | $59.78 | Total: $1,494.50 |
| 1 | 50 | $50.96 | Total: $2,548.00 |
| 1 | 100 | $44.10 | Total: $4,410.00 |
Overview
ARN25068 is a potent inhibitor of GSK-3?, FYN, and DYRK1A protein kinases, exerting its activity in the sub-micromolar range. This compound effectively addresses tau hyperphosphorylation [1].
Chemical Properties
| Molecular Formula | C19H18N6S |
| Molecular Weight | 362.45 |
| CAS Numbers | 2649882-80-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C1=C2C(=NC(NCC3=CC=CC=C3)=N1)C=CS2)C=4C=C(NN4)C5CC5 |
Storage and Handling
0C Short Term, -20C Long Term
References
Demuro S, et al. ARN25068, a versatile starting point towards triple GSK-3?FYNDYRK1A inhibitors to tackle tau-related neurological disorders. Eur J Med Chem. 2022;229 114054.