Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
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- TNF Receptors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.05 | Total: $140.25 |
| 1 | 10 | $23.76 | Total: $237.60 |
| 1 | 25 | $20.13 | Total: $503.25 |
| 1 | 50 | $17.16 | Total: $858.00 |
| 1 | 100 | $14.85 | Total: $1,485.00 |
Overview
NF-?BMAPK-IN-1 is a potent dual inhibitor of the NF-?B and MAPK pathways with potential anti-inflammatory activity, inhibition of NO production, and inhibition of LPS-induced activation of iNOS, COX-2, ER? and P38. NF-?BMAPK-IN-1 is used for the prevention and treatment of rheumatoid arthritis (RA).
Chemical Properties
| Molecular Formula | C27H27NO7 |
| Molecular Weight | 477.51 |
| CAS Numbers | 2413940-56-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(C1=C(C(C)=O)C=CC(OC)=C1)C2=CC=C(NC(C=CC3=CC(OC)=C(OC)C(OC)=C3)=O)C=C2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Hu YS, et al. Novel paeonol derivatives Design, synthesis and anti-inflammatory activity in vitro and in vivo. Bioorg Chem. 2020 May;98 103735.