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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $141.95 | Total: $709.75 |
| 1 | 10 | $120.24 | Total: $1,202.40 |
| 1 | 25 | $101.87 | Total: $2,546.75 |
| 1 | 50 | $86.84 | Total: $4,342.00 |
| 1 | 100 | $75.15 | Total: $7,515.00 |
Overview
mTOR inhibitor 9f is a selective mTOR inhibitor with IC50 of 1.25nM and 82nM for mTOR and PI3K?, respectively.
Chemical Properties
| Molecular Formula | C25H23N5O2S |
| Molecular Weight | 457.55 |
| CAS Numbers | 1144075-42-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C(NC1=CC=CC=C1)=O)C2=CC=C(C3=NC(=C4C(=N3)C=CS4)N5CC6OC(C5)CC6)C=C2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Verheijen JC, et al. Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K. Bioorg Med Chem Lett. 2010 Jan 1;20[1] 375-9.