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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $93.50 | Total: $467.50 |
| 1 | 10 | $79.20 | Total: $792.00 |
| 1 | 25 | $67.10 | Total: $1,677.50 |
| 1 | 50 | $57.20 | Total: $2,860.00 |
| 1 | 100 | $49.50 | Total: $4,950.00 |
Overview
Casein kinase 1?-IN-6 is a potent and selective inhibitor of the protein kinase CK-1? with an IC50 of 23 nM, demonstrating neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays. Casein kinase 1?-IN-6 can be used to study neurodegenerative diseases.
Chemical Properties
| Molecular Formula | C16H10ClF3N2OS |
| Molecular Weight | 370.78 |
| CAS Numbers | 1579991-01-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C(CC1=CC(Cl)=CC=C1)=O)C=2SC=3C(N2)=CC=C(C(F)(F)F)C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Morales-Garcia JA, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1? Inhibitors in Models of Parkinson's Disease. ACS Omega. 2017;2[8] 5215-5220.