Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $41.65 | Total: $208.25 |
| 1 | 10 | $35.28 | Total: $352.80 |
| 1 | 25 | $29.89 | Total: $747.25 |
| 1 | 50 | $25.48 | Total: $1,274.00 |
| 1 | 100 | $22.05 | Total: $2,205.00 |
Overview
FAK-IN-10 is an inhibitor of FAK (IC50: 76.3 ?M) and demonstrates antitumor activity in MCF-7 and A431 cell lines with IC50 values of 4.23 ?M and 0.78 ?M, respectively.
Chemical Properties
| Molecular Formula | C15H10BrN3O2S |
| Molecular Weight | 376.23 |
| CAS Numbers | 491839-65-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(C1=CC=C(Br)C=C1)CSC2=NN=C(O2)C=3C=CN=CC3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Zhang LR, et al. Synthesis, biological evaluation and molecular docking studies of novel 2-[1,3,4-oxadiazol-2-ylthio]-1-phenylethanone derivatives. Bioorg Med Chem. 2012 Jun 1;20[11] 3615-21.