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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $70.55 | Total: $352.75 |
| 1 | 10 | $59.76 | Total: $597.60 |
| 1 | 25 | $50.63 | Total: $1,265.75 |
| 1 | 50 | $43.16 | Total: $2,158.00 |
| 1 | 100 | $37.35 | Total: $3,735.00 |
Overview
Senexin B is a potent and selective inhibitor of CDK819(CDK8 and CDK19 with Kds of 140 nM and 80 nM).
Chemical Properties
| Molecular Formula | C27H26N6O |
| Molecular Weight | 450.53 |
| CAS Numbers | 1449228-40-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN1CCN(CC1)C(=O)c1ccc2cc(CCNc3ncnc4ccc(cc34)C#N)ccc2c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Porter D, et al. Abstract PR08 Targeting tumor microenvironment with selective small-molecule inhibitors of CDK819. Abstracts AACR Special Conference on Cellular Heterogeneity in the Tumor Microenvironment; 2014 Feb 26-Mar 1; San Diego, CA. Philadelphia [PA] AACR; Cancer Res 2015;75[1 Suppl] Abstract nr PR08. doi 10.11581538-7445.CHTME14-PR08