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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $63.75 | Total: $318.75 |
| 1 | 10 | $54.00 | Total: $540.00 |
| 1 | 25 | $45.75 | Total: $1,143.75 |
| 1 | 50 | $39.00 | Total: $1,950.00 |
| 1 | 100 | $33.75 | Total: $3,375.00 |
Overview
CHIKV-IN-2, a chemical compound, exhibits potent inhibitory activity against the enzyme Dihydroorotate Dehydrogenase (DHODH), crucial for pyrimidine synthesis affecting various viruses' replication. It serves as an effective Chikungunya virus (CHIKV) inhibitor, demonstrating significant cellular antiviral activity (EC90=270 nM) and enhanced liver microsomal stability[1].
Chemical Properties
| Molecular Formula | C23H26N2O2 |
| Molecular Weight | 362.46 |
| CAS Numbers | 2361289-44-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc2CCCCCc2cc1C(=O)Nc1ccc(cc1)C(C)(C)C#N |
Storage and Handling
0C Short Term, -20C Long Term
References
Ahmed SK, et, al. Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors. J Med Chem. 2021 Apr 22;64[8] 4762-4786.