Categories
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- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $93.50 | Total: $467.50 |
| 1 | 10 | $79.20 | Total: $792.00 |
| 1 | 25 | $67.10 | Total: $1,677.50 |
| 1 | 50 | $57.20 | Total: $2,860.00 |
| 1 | 100 | $49.50 | Total: $4,950.00 |
Overview
HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM).
Chemical Properties
| Molecular Formula | C24H22N6O4 |
| Molecular Weight | 458.47 |
| CAS Numbers | 2320462-65-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnco4)c(N[C@H](CO)c4ccccc4)n3)cc12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Degnan AP, et al. Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1. ACS Med Chem Lett. 2021;12[3] 443-450. Published 2021 Feb 19.