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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $53.55 | Total: $267.75 |
| 1 | 10 | $45.36 | Total: $453.60 |
| 1 | 25 | $38.43 | Total: $960.75 |
| 1 | 50 | $32.76 | Total: $1,638.00 |
| 1 | 100 | $28.35 | Total: $2,835.00 |
Overview
PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3? enzyme assay and 1.1 nM based on ADP-Glo assay. It shows desirable central nervous system (CNS) properties and potency. It is equally effective at inhibition of the two known GSK-3 isoforms (GSK-3? and GSK-3?) with IC50 values of 10.0 and 9.0 nM in mobility shift assays, respectively.
Chemical Properties
| Molecular Formula | C16H16ClN5O3 |
| Molecular Weight | 361.78 |
| CAS Numbers | 1962178-27-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ccc(cc1Cl)-c1ocnc1C(=O)NCCCn1cncn1 |
Storage and Handling
0C Short Term, -20C Long Term