KO-947

KO-947

ATQ0005

CAS 1695533-89-1

More details

1000 Items

$59.80

$59.80 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $39.10 Total: $195.50
110 $33.12 Total: $331.20
125 $28.06 Total: $701.50
150 $23.92 Total: $1,196.00
1100 $20.70 Total: $2,070.00

Overview

KO-947 is a potent and specific ERK12 kinase inhibitor.

Chemical Properties

Molecular FormulaC21H17N5O
Molecular Weight355.39
CAS Numbers1695533-89-1
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1Nc2cc3[nH]nc(-c4ccncc4)c3cc2CN1Cc1ccccc1

Storage and Handling

0C Short Term, -20C Long Term

References

Burrows F, et al. KO-947, a potent ERK inhibitor with robust preclinical single agent activity in MAPK pathway dysregulated tumors [abstract]. In Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia [PA] AACR; Cancer Res 2017;77[13 Suppl] Abstract nr 5168. doi 10.11581538-7445.AM2017-5168.