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Overview
Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-1 infection.
Chemical Properties
| Molecular Formula | C13H17NO8 |
| Molecular Weight | 315.28 |
| CAS Numbers | 1335210-23-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C(OC)OC)N1C(C(OC)=O)=C(OC)C(=O)C(C(O)=O)=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Sivaram Prasad, et al. Process for the preparation of dolutegravir . WO 2016125192 A2.