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Overview
2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)
Chemical Properties
| Molecular Formula | C5H3N3 |
| Molecular Weight | 105.1 |
| CAS Numbers | 14080-23-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N#CC1=NC=CC=N1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Rankovic Z , Cai J , Kerr J , et al. Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K Improving selectivity over hERG[J]. Bioorganic and Medicinal Chemistry Letters, 2010, 20[21] 6237-6241.