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Overview
5,6-Dimethyl-1H-benzo[d]imidazole (5,6-Dimethylbenzimidazole) is an intermediate in Riboflavin metabolism and is the penultimate step in the synthesis of alpha-Ribazole. It is converted from Riboflavin and subsequently transformed into N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole by the enzyme nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21).
Chemical Properties
| Molecular Formula | C9H10N2 |
| Molecular Weight | 146.19 |
| CAS Numbers | 582-60-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | |
| InChl Key | |
| InChl Code | |
| SMILES Code | Cc1cc2nc[nH]c2cc1C |
Storage and Handling
0C Short Term, -20C Long Term
Synonyms
References
Sreekumar A , Poisson L M , Rajendiran T M , et al. Corrigendum Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression[J]. Nature, 2009, 457[7231] 910-914.