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Overview
Fomepizole (4-Methylpyrazole) is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole(4-Methylpyrazole) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Chemical Properties
| Molecular Formula | C4H6N2 |
| Molecular Weight | 82.1 |
| CAS Numbers | 7554-65-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | |
| InChl Key | |
| InChl Code | |
| SMILES Code | CC1=CNN=C1 |
Storage and Handling
0C Short Term, -20C Long Term
Synonyms
References
Nagata H, et al. Am J Physiol. 1996 Dec;271[6 Pt 1] G1028-33.