5-Methyluridine

5-Methyluridine

AT5282

CAS 1463-10-1

More details

1000 Items

$35.00

$35.00 per 500 mg

Overview

5-Methyluridine (Thymine riboside) is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls.DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents.

Chemical Properties

Molecular FormulaC10H14N2O6
Molecular Weight258.23
CAS Numbers1463-10-1
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(C)=C2

Storage and Handling

0C Short Term, -20C Long Term

References

Morris GS, et al. Use of biological fluids for the rapid diagnosis of potentially lethal inherited disorders of human purine and pyrimidine metabolism. Biomed Chromatogr. 1986 Jun;1[3] 109-18.