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Overview
Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is also found to be associated with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency, another inborn error of metabolism.
Chemical Properties
| Molecular Formula | C6H10O4 |
| Molecular Weight | 146.14 |
| CAS Numbers | 626-51-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C(CC(O)=O)C)C(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Sreekumar A , Poisson L M , Rajendiran T M , et al. Corrigendum Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression[J]. Nature, 2009, 457[7231] 910-914.