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Overview
3-(Methylthio)propionic acid (4-Thiapentanoic acid) is one of the metabolites of methionine (especially of D-methionine). Cultures of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid in amounts directly related to the concentration of methionine in the medium. The first intermediate in the pathway may be the keto acid, which is then oxidatively decarboxylated to 3-methylthiopropionic acid.
Chemical Properties
| Molecular Formula | C4H8O2S |
| Molecular Weight | 120.17 |
| CAS Numbers | 646-01-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CSCCC(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Surette R, et al. Formation of 3-methylthioacrylic acid from methionine by Streptomyces lincolnensis. Isolation of a peroxidase. J Antibiot [Tokyo]. 1976 Jun;29[6] 646-52.