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Overview
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels, resulting in central nervous system toxicity. This causes hyperexcitation of contaminated insects' nerves and muscles. Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also because GluCl channels do not exist in mammals.
Chemical Properties
| Molecular Formula | C12H4Cl2F6N4OS |
| Molecular Weight | 437.15 |
| CAS Numbers | 120068-37-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC=1N(N=C(C#N)C1S(C(F)(F)F)=O)C2=C(Cl)C=C(C(F)(F)F)C=C2Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
Zaluski R, et al. Environ Toxicol Chem. 2015 May;34[5] 1062-9.