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Overview
Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis andor catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction.
Chemical Properties
| Molecular Formula | C8H10NO6P |
| Molecular Weight | 247.14 |
| CAS Numbers | 54-47-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(OP(=O)(O)O)C=1C(C=O)=C(O)C(C)=NC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Modak MJ. Pyridoxal 5' phosphate a selective inhibitor of oncornaviral DNA polymerases. Biochem Biophys Res Commun. 1976 Jul 12;71[1] 180-7.