Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $65.45 | Total: $327.25 |
| 1 | 10 | $55.44 | Total: $554.40 |
| 1 | 25 | $46.97 | Total: $1,174.25 |
| 1 | 50 | $40.04 | Total: $2,002.00 |
| 1 | 100 | $34.65 | Total: $3,465.00 |
Overview
EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylaseC17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage enzyme-selective compound with potential anti-androgenic and anti-tumor activity.
Chemical Properties
| Molecular Formula | C16H13FN2OS |
| Molecular Weight | 300.35 |
| CAS Numbers | 1429329-63-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C)(O)(C=1SC(=NC1)C2=CC=C(F)C=C2)C=3C=CN=CC3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Rao N S, et al. ASN001, a novel CYP17 lyase inhibitor, in men with metastatic castration-resistant prostate cancer [mCRPC] Safetytolerability and early activity in a multicenter phase 12 trial. 2016.