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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $225.25 | Total: $1,126.25 |
| 1 | 10 | $190.80 | Total: $1,908.00 |
| 1 | 25 | $161.65 | Total: $4,041.25 |
| 1 | 50 | $137.80 | Total: $6,890.00 |
| 1 | 100 | $119.25 | Total: $11,925.01 |
Overview
7-Hydroxymethotrexate is the major metabolite of Methotrexate.Methotrexate is an inhibitor of folic acid, inhibiting dihydrofolate reductase, which prevents the conversion of folic acid to tetrahydrofolate, and inhibiting DNA synthesis.Methotrexate is also an inhibitor of metabolism.
Chemical Properties
| Molecular Formula | C20H22N8O6 |
| Molecular Weight | 470.44 |
| CAS Numbers | 5939-37-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC1=C2C(NC(=O)C(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=NC(N)=N1 |
Storage and Handling
0C Short Term, -20C Long Term
References
L Fahrig, et al. Pharmacokinetics of methotrexate [MTX] and 7-hydroxymethotrexate [7-OH-MTX] in rats and evidence for the metabolism of MTX to 7-OH-MTX. Cancer Chemother Pharmacol. 1989;23[3] 156-60.