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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $96.05 | Total: $480.25 |
| 1 | 10 | $81.36 | Total: $813.60 |
| 1 | 25 | $68.93 | Total: $1,723.25 |
| 1 | 50 | $58.76 | Total: $2,938.00 |
| 1 | 100 | $50.85 | Total: $5,085.00 |
Overview
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 ?M).
Chemical Properties
| Molecular Formula | C27H31N7O2 |
| Molecular Weight | 485.58 |
| CAS Numbers | 1421373-99-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(N(CCNC)C)C(NC(C=C)=O)=C4)=NC=C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Finlay MR, et al. Discovery of a potent and selective EGFR inhibitor [AZD9291] of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem. 2014 Oct 23;57[20] 8249-67.