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Overview
5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative and a metabolite of the antineoplastic agents BIC and DIC. It serves as a condensation agent in the preparation of nucleosides and nucleotides, and when compounded with orotic acid, it is used to treat liver diseases.
Chemical Properties
| Molecular Formula | C4H6N4O |
| Molecular Weight | 126.12 |
| CAS Numbers | 360-97-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC(=O)C1=C(N)NC=N1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Pastore S, et al. Rheumatol Int. 2015 Apr;35[4] 619-27.