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Overview
2,2-Dihydroxyacetic acid (Formylformic acid) is an intermediate in the glyoxalate cycle, which enables certain organisms to convert fatty acids to carbohydrates.2,2-Dihydroxyacetic acid has been found to be associated with primary hyperoxaluria, an inborn error of metabolism. As an aldehyde, glyoxalate is also highly active and can modify proteins to form advanced glycosylation products (AGEs).
Chemical Properties
| Molecular Formula | C2H4O4 |
| Molecular Weight | 92.05 |
| CAS Numbers | 563-96-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C(O)=O)(O)O |
Storage and Handling
0C Short Term, -20C Long Term
References
Lee S H , Kim S O , Chung B C . Gas chromatographic–mass spectrometric determination of urinary oxoacids using O-[2,3,4,5,6-pentafluorobenzyl]oxime-trimethylsilyl ester derivatization and cation-exchange chromatography[J]. Journal of Chromatography B, 1998, 719[1-2] 1-7.